| Issue | #4 |
| Published | April 1975 |
| Cover Price | 0.50 |
| Pages | 68 |
| Editing | Len Wein |
| Notes | Letters page replies by Steve Gerber. Possible Giacoia cover inker credit provided 2006 by Nick Caputo. |
| Characters | Defenders [Hulk [Bruce Banner]; Dr. Strange [Stephen Strange]; Nighthawk [Kyle Richmond]]; Squadron Sinister [Hyperion; Whizzer; Dr. Spectrum]; Yellowjacket [Dr. Hank Pym] |
| Genre | superhero |
| Pencils | Gil Kane |
| Inks | Mike Esposito; Frank Giacoia? |
| Letters | Gaspar Saladino |
| Notes | Letters page replies by Steve Gerber. Possible Giacoia cover inker credit provided 2006 by Nick Caputo. |
| Reprinted | In Essential Defenders (Marvel, 2005 series) #2 |
| Characters | Defenders [Nighthawk [Kyle Richmond]; Dr. Strange [Stephen Strange]; Valkyrie; Hulk [Bruce Banner]]; Trixie Starr [also as Trish Starr]; Dr. James Wynter; Yellowjacket [Dr. Hank Pym]; Wasp [Janet Van Dyne]; Egghead; Aragorn; Squadron Sinister [Hyperion; Whizzer; Dr. Spectrum] |
| Synopsis | The Defenders and Yellowjacket are on the trail of Egghead, who planted a bomb in the car of Kyle Richmond and injured both Richmond and Trixie Starr. |
| Genre | superhero |
| Script | Steve Gerber (plot, script); Don McGregor (plot assist); Roger Slifer (plot assist) |
| Pencils | Don Heck |
| Inks | Vince Colletta |
| Colors | Petra Goldberg |
| Letters | Gaspar Saladino (page 1); Dave Hunt |
| Notes | Trish Starr loses her left arm. McGregor and Slifer credits from the letters page to Giant-Size Defenders #5. |
| Reprinted | In Essential Defenders (Marvel, 2005 series) #2 |
| Characters | Sub-Mariner |
| Genre | superhero |
| Script | Bill Everett |
| Pencils | Bill Everett |
| Inks | Bill Everett |
| Letters | Bill Everett? |
| Notes | In the comic, the story is misidentified as coming from Human Torch (1940 series) #4. |
| Reprinted | from Human Torch, The (Marvel, 1940 series) #3 (Winter 1940-1941) |
| Characters | F: Doctor Strange; V: Baron Mordo |
| Genre | superhero |
| Script | Stan Lee |
| Pencils | Steve Ditko |
| Inks | Steve Ditko |
| Letters | Artie Simek |
| Reprinted | from Strange Tales (Marvel, 1951 series) #121 (June 1964) |