| Issue | #1 |
| Published | July 2006 |
| Cover Price | 2.95 USD |
| Pages | 36 |
| Editing | Gary Carlson; Chris Ecker; Edward DeGeorge |
| Notes | Jack Cole Plastic Man tribute. |
| Characters | Protoplasman; Knight Watchman; Miss Firecracker |
| Genre | Superhero; Humor |
| Script | Mark Lewis |
| Pencils | Mark Lewis |
| Inks | Mark Lewis |
| Colors | Mark Lewis |
| Letters | Mark Lewis |
| Notes | Jack Cole Plastic Man tribute. |
| Script | Gary Carlson |
| Pencils | Mark Lewis; Mort Todd |
| Inks | Mark Lewis; Mort Todd |
| Letters | typeset |
| Notes | Credits page done in the style of 1970's Warren magazines, which published The Spirit reprints at the time. Includes reproduction of cover & panel from this issue's Protoplasman story. |
| Characters | Prof. Igor Eisner; Julius Clifford (crooked assitant); Knight Watchman; Whitey Schwartz (kid sidekick); Sheik Ali Ghatar [Moe Goldberg] (actor); The Alligator (European master spy); Albert (pet alligator) |
| Genre | Super-hero |
| Script | Gary Carlson |
| Pencils | Jeff Austin |
| Inks | Jeff Austin |
| Letters | Jeff Austin |
| Notes | Will Eisner Spirit tribute; Prof. Eisner is a dead ringer for Commissioner Dolan. |
| Script | Gary Carlson |
| Pencils | Mort Todd; Bill Fugate; ? |
| Inks | Mort Todd; Bill Fugate; ? |
| Letters | typeset |
| Notes | Gary Carlson discusses Big Bang's departure from Image Comics and upcoming Big Bang stories. |
| Characters | Dr. Noah Toll (noted chemist); Mint Julip; Protoplasman; Willie Wampum (The Indian Rubber Man) |
| Genre | Superhero; Humor |
| Script | Gary Carlson |
| Pencils | Mort Todd |
| Inks | Mort Todd |
| Letters | Mort Todd |
| Notes | Jack Cole Plastic Man tribute. First appearance of Protoplasman. |
| Characters | Wildman; Rubberoy |
| Script | Gary Carlson |
| Pencils | Richard "Grass" Green |
| Inks | Richard "Grass" Green |
| Letters | typeset |
| Notes | Gary Carlson discusses the evolution of Protoplasman. Includes panels from Wildman & Ruberoy, plus illustration of Spastic Man. |
| Genre | Superhero; Humor |
| Script | Gary Carlson |
| Pencils | Mort Todd |
| Inks | Mort Todd |
| Letters | typeset |
| Notes | Ad for Protoplasman merchandise at www.cafepress.com/protoplasman, www.bigbangcomics.com, and www.comicfix.com. |
| Characters | Victoria Frankenstein (biomedical researcher); William Frankenstein (brother); Frankenstein |
| Genre | Superhero; Monster |
| Script | Bill Fugate |
| Pencils | Bill Fugate |
| Inks | Bill Fugate |
| Letters | Bill Fugate |
| Notes | Preview and first appearance of Super Frankenstein. Full story appears in Big Bang Presents (Big Bang, 2006 series) #2 (September 2006). |
| Characters | Miss Firecracker ("Uncle Sam's Favorite Niece") |
| Genre | Superhero |
| Script | Mike Worley |
| Pencils | Mike Worley |
| Inks | Jeff Austin |
| Letters | Jeff Austin |
| Characters | Protoplasman; Willie Wampum; Mint Julip |
| Genre | Superhero; Humor |
| Script | Gary Carlson |
| Pencils | Mort Todd |
| Inks | Mort Todd |
| Colors | Mort Todd |
| Letters | Mort Todd |
| Notes | On back cover. Jack Cole Plastic Man and Police Comics tribute. |