| Issue | #105 |
| Published | [April] 2005 |
| Cover Price | 2.99 USD; 3.99 CAD |
| Pages | 36 |
| Editing | Bill Morrison; Terry Delegeane (managing editor) |
| Characters | Homer Simpson; Dr. Nick Riviera |
| Genre | Humor; Sitcom; Family |
| Pencils | Jason Ho (signed) |
| Inks | Mike Rote (signed) |
| Colors | Nathan Kane (signed) |
| Characters | Homer Simpson; Marge Simpson; Bart Simpson; Lisa Simpson; Maggie Simpson; Dr. Nick Riviera; Dr. Julius Hibbert; Principal Skinner; Dolph; Jimbo Jones; Ralph Wiggum; Milhouse van Houten; Gil; Snake; Otto Mann; Hans Moleman |
| Synopsis | The local Board of Health calls Dr. Nick's irresponsible medical procedures and ill-advised cosmetic quackery into question, but all is not as it seems, and the "good" doctor may serve a purpose in the medical establishment that few are willing to admit, unless those few decide to visit "Dr. Nick at Nite." [per solicitation] |
| Genre | Humor; Sitcom; Family |
| Script | Ian Boothby |
| Pencils | Phil Ortiz |
| Inks | Phyllis Novin |
| Colors | Art Villanueva |
| Letters | Karen Bates |
| Notes | This story is a framing sequence for the 3 following stories. This story has 2.67 pages at the beginning and 1.33 pages at the end of the book. |
| Characters | Patty Bouvier; Selma Bouvier; Edna Krabappel; Luann van Houten; Agnes Skinner; Pierre; Moe Szyslak; Homer Simpson; Marge Simpson; Bart Simpson; Lisa Simpson; Maggie Simpson |
| Synopsis | Dr. Nick helps Selma and Patty fix a hair problem. |
| Genre | Humor; Sitcom; Family |
| Script | Ian Boothby |
| Pencils | Phil Ortiz |
| Inks | Phyllis Novin |
| Colors | Art Villanueva |
| Letters | Karen Bates |
| Characters | Comic Book Guy; Dr. Nick Riviera; Kirk van Houten; Milhouse van Houten; Database; Dr. Nick Riviera; Nelson Muntz; Bart Simpson; Professor Frink |
| Synopsis | Comic Book Guy injures his brain in a fall, and it's up to Dr. Nick to give him a brain transplant so he can return to normal. |
| Genre | Humor; Sitcom; Family |
| Script | Ian Boothby |
| Pencils | Phil Ortiz |
| Inks | Phyllis Novin |
| Colors | Art Villanueva |
| Letters | Karen Bates |
| Reprinted | in Bongo Comics (Bongo, 2006 series) #[nn] |
| Characters | Krusty the Clown; Mr. Teeny; Chief Wiggum; Officer Eddie; Dr. Nick Riviera; Professor Frink; Sideshow Mel |
| Synopsis | Dr. Nick is needed to help stop clown zombies. |
| Genre | Humor; Sitcom; Family |
| Script | Ian Boothby |
| Pencils | Phil Ortiz |
| Inks | Phyllis Novin |
| Colors | Art Villanueva |
| Letters | Karen Bates |
| Letters | typeset |
| Notes | Letters and fan art from readers - Alex Meseck and Josephine Bay. |