| Issue | #3 |
| Published | December 2008 |
| Cover Price | 2.99 USD |
| Pages | 36 |
| Editing | Axel Alonso; Jody Leheup (Assistant) |
| Characters | Deadpool; Skrulls; Super Skrull |
| Genre | superhero |
| Pencils | Clayton Crain (Painted) |
| Inks | Clayton Crain (Painted) |
| Colors | Clayton Crain (Painted) |
| Letters | Typeset |
| Characters | Deadpool; Super Skrull |
| Genre | superhero |
| Pencils | Ian Churchill |
| Letters | Typeset |
| Characters | Deadpool |
| Genre | superhero |
| Pencils | Paco Medina |
| Inks | Juan Vlasco |
| Colors | Marte Gracia |
| Letters | Typeset |
| Notes | 2nd print variant utilizes an interior splash page as the cover image. |
| Genre | superhero |
| Pencils | Paco Medina |
| Inks | Juan Vlasco |
| Colors | Marte Gracia |
| Letters | Typeset |
| Characters | FEATURE: Deadpool; GUEST: Nick Fury; VILLAINS: Skrulls; Super Skrull; Skrull Deadpools; CAMEO: Norman Osborn |
| Synopsis | On orders from Fury, Deadpool makes quick work of the Skrulls he was supposedly working for; The cloned Skrull Deadpools crash thanks to the cancer in Wade's system; DP downloads Skrull info for Fury but it is intercepted by Norman Osborn. |
| Genre | superhero |
| Script | Daniel Way |
| Pencils | Paco Medina |
| Inks | Juan Vlasco |
| Colors | Marte Gracia |
| Letters | Virtual Calligraphy's Cory Petit |
| Characters | Deadpool |
| Genre | superhero |
| Pencils | Jason Pearson |
| Inks | Jason Pearson |
| Letters | Typeset |
| Notes | Full page cover art for next issue. |