| Issue | #3 |
| Published | December 2008 |
| Frequency | monthly |
| Cover Price | 2.99 USD; 3.50 CAN |
| Pages | 36 |
| Editing | Nick Lowe; Daniel Ketchum (assistant) |
| Characters | Chase Stein; Molly Hayes |
| Pencils | Humberto Ramos (signed) |
| Inks | Humberto Ramos (signed) |
| Synopsis | An advertisement for Microsoft's computer game, "Gears of War 2." |
| Notes | inside front cover |
| Letters | typeset |
| Characters | Chase Stein; Molly Hayes; Nico Minoru; Karolina Dean; Victor Mancha; Xavin; Klara; Old Lace; VaDanti; Val; VaRikk |
| Synopsis | The team deals with the consequences of Nico's "scatter" spell. |
| Genre | superhero |
| Script | Terry Moore |
| Pencils | Humberto Ramos |
| Inks | Dave Meikis |
| Colors | Christina Strain |
| Letters | Joe Caramagna [as VC's Joe Caramagna] |
| Synopsis | An anti-illegal drug use advertisement from the Office of National Drug Control Policy. |
| Notes | This advertisement is between pages 3 and 4 of the Runaways story. |
| Synopsis | An advertisement for 2K Games' computer game, "Bioshock." |
| Notes | This advertisement is between pages 8 and 9 of the Runaways story. |
| Synopsis | An advertisement for Blizzard Entertainment's trading card game, "World of Warcraft: Drums of War." |
| Notes | This advertisement is between page 11 of the Runaways story and the "Embrace Change" promotional. |
| Synopsis | An in-house promotional advertisement for Marvel's event, "Secret Invasion," featuring two human children and one Skrull child. |
| Notes | This advertisement is between the "Worlds of Warcraft" advertisement and page 12 of the Runaways story. |
| Synopsis | An advertisement for comics retailer, Midtown Comics. |
| Notes | This advertisement is between page 16 of the Runaways story and the "Fable II" advertisement. |
| Synopsis | An advertisement for Microsoft's computer game, "Fable II." |
| Notes | This advertisement is between the Midtown Comics advertisement and page 17 of the Runaways story. |
| Synopsis | An in-house promotional advertisement for Captain America: White (Marvel, 2008 series). |
| Notes | This advertisement is between pages 17 and 18 of the Runaways story. |
| Synopsis | An advertisement for X-Men and Spider-Man (Marvel, 2008 series). |
| Notes | This advertisement is between pages 18 and 19 of the Runaways story. |
| Synopsis | An advertisement from America's Milk Processors promoting milk consumption, featuring professional basketball play Dwight Howard. |
| Notes | This advertisement follows the final page of the Runaways story and is on the inside back cover. |
| Synopsis | An advertisement for Old Spice's Red Zone body wash. |
| Notes | back cover. |