| Issue | #573 |
| Published | December 2008 |
| Cover Price | 3.99 USD |
| Pages | 52 |
| Editing | Stephen Wacker; Thomas Brennan (Assistant) |
| Characters | Green Goblin [Norman Osborn] |
| Genre | superhero |
| Pencils | John Romita Jr. |
| Inks | Klaus Janson |
| Colors | Dean White |
| Letters | Typeset |
| Characters | Scorpion [Mac Gargan; Venom] |
| Genre | superhero |
| Pencils | Kevin Maguire |
| Inks | Kevin Maguire |
| Letters | Typeset |
| Characters | Zombie Spider-Man; Zombie Green Goblin |
| Genre | superhero |
| Pencils | Marko Djurdjevic (Painted) |
| Inks | Marko Djurdjevic (Painted) |
| Colors | Marko Djurdjevic (Painted) |
| Letters | Typeset |
| Characters | Spider-Man; Stephen Colbert |
| Genre | superhero |
| Pencils | Joe Quesada |
| Inks | Joe Quesada |
| Letters | Typeset |
| Genre | superhero |
| Pencils | John Romita Jr. |
| Inks | Klaus Janson |
| Colors | Dean White |
| Letters | Typeset |
| Characters | Spider-Man; GUESTS: Aunt May Parker; Green Goblin [Norman Osborn]; Anti-Venom [Eddie Brock]; Ben Urich; Sally Floyd; Lily Hollister; Betty Brant; Martin Li; Thunderbolts [Songbird; Venom [Mac Gargan; also as Scorpion]; Bullseye; Radioactive Man] |
| Synopsis | Norman invites Harry to rule the world with him as father and son; Spider-Man and Anti-Venom take on Green Goblin and the Thunderbolts; Gargan injects Anti-Venom with a deadly poison which causes the suit to leave Eddie; Spidey discovers that it was Harry and not Norman that was doing medical experiments on illegal immigrants; Norman spins recent events in the media to make himself look good; Lily kisses Peter; Aunt May sees a violent side of Martin Li that she didn't expect; Eddie finds that the poison's effect is temporary and heads off into his new life as Anti-Venom. |
| Genre | superhero |
| Script | Dan Slott |
| Pencils | John Romita Jr. |
| Inks | Klaus Janson |
| Colors | Dean White |
| Letters | Virtual Calligraphy's Cory Petit |
| Characters | Spider-Man; GUESTS: Stephen Colbert; J. Jonah Jameson; VILLAIN: Grizzly |
| Synopsis | Spidey inspires presidential hopeful Stephen Colbert to stay in the race. |
| Genre | superhero |
| Script | Mark Waid |
| Pencils | Patrick Olliffe |
| Inks | Serge LaPointe |
| Colors | Rain Beredo |
| Letters | Virtual Calligraphy's Cory Petit |