| Issue | #580 |
| Published | February 2009 |
| Frequency | thrice monthly |
| Cover Price | 2.99 USD |
| Pages | 36 |
| Editing | Stephen Wacker; Tom Brennan (assistant); Tom Brevoort (executive) |
| Characters | Spider-Man |
| Genre | superhero |
| Pencils | Lee Weeks |
| Inks | Lee Weeks |
| Synopsis | An advertisement for BVD's men's underwear, available at J.C. Penney. |
| Notes | inside front cover |
| Letters | typeset |
| Characters | Spider-Man; May Parker; the Blank; Ray Donovan; Joe Robertson |
| Synopsis | Spider-Man takes a personal interest in bringing in the bank-robbing Blank. |
| Genre | super-hero |
| Script | Roger Stern |
| Pencils | Lee Weeks |
| Inks | Lee Weeks |
| Colors | Dean White |
| Letters | Cory Petit [as VC's Cory Petit] |
| Synopsis | An advertisement for Erin Hunter's Warriors novels. |
| Notes | This advertisement is between pages 3 and 4 of the Spider-Man story. |
| Synopsis | An advertisement for Dr. Fresh's Firefly children's toothbrushes. |
| Notes | This advertisement is between pages 8 and 9 of the Spider-Man story. |
| Synopsis | An advertisement for the Activision computer game, "Spider-Man Web of Shadows" |
| Notes | This advertisement is between pages 12 and 13 of the Spider-Man story. |
| Synopsis | An advertisement for Giant Merchandising's Heroes and Villains t-shirts, featuring licensed Marvel and DC characters. |
| Notes | This advertisement is between page 12 of the Spider-Man story and the Marvel Mini-mates advertisement. |
| Synopsis | An advertisement for Diamond Select Toys' Art Asylum Marvel Mini-Mates toys, featuring licensed Marvel characters. |
| Notes | This advertisement is between the Giant Merchandise t-shirt advertisement and page 13 of the Spider-Man story. |
| Synopsis | An in-house promotional advertisement for War Machine (Marvel, 2008 series). |
| Notes | This advertisement is between pages 18 and 19 of the Spider-Man story. |
| Synopsis | An in-house promotional advertisement for War of Kings: Who Will Rule? (Marvel, 2009 series). |
| Notes | This advertisement is between pages 19 and 20 of the Spider-Man story. |
| Synopsis | Letters of comment from Roger Stern; Joel Johnson, Omaha NE; Eric Hodge; C. Charles Dodson; and Julian Staton. |
| Script | Steve Wacker |
| Letters | typeset |
| Notes | This letters column follows the final page of the Spider-Man story. |
| Synopsis | An advertisement for Imperial's finger-board toys, featuring licensed Marvel characters. |
| Notes | Inside back cover |
| Synopsis | An advertisement for 2x2's toothbrush holders, featuring licensed Marvel characters. |
| Notes | back cover |