| Issue | #559 |
| Published | September 2008 |
| Frequency | monthly |
| Cover Price | 2.99 USD; 3.05 CAN |
| Pages | 36 |
| Editing | Tom Brevoort; Jeanine Schaefer (associate) |
| Characters | Bruce Robert Banner, Jr.; Alex Ultron; Lightwave; Natalie X; the Hooded Man; Psionics; Mr. Fantastic; Dr. Doom |
| Genre | superhero |
| Pencils | Bryan Hitch |
| Inks | Andrew Curre ? |
| Letters | typeset |
| Synopsis | A recruitment advertisement for the US Navy. |
| Notes | inside front cover |
| Letters | typeset |
| Characters | the Thing; Deborah Green; Human Torch [Johnny Storm]; Miguel; Red-Beard; Lightwave; Invisible Woman; Alyssa Moy; Psionic; the Hooded Man; Mr. Fantastic; Henry Pym; Valeria Richards; Mrs. Deneuve; Dr. Doom; Galactus; Bruce Robert Banner, Jr. |
| Synopsis | Johnny is attacked and captured by three unknown super-beings. |
| Genre | superhero |
| Script | Mark Millar |
| Pencils | Bryan Hitch |
| Inks | Bryan Hitch; Andrew Currie |
| Colors | Paul Mounts |
| Letters | Rus Wooton [as VC's Rus Wooton] |
| Synopsis | An advertisement for Microsoft's computer game, "Too Human." |
| Notes | This advertisement is between pages 1 and 2 of the Fantastic Four story. |
| Synopsis | An advertisement for Upper Deck's Marvel trading cards. |
| Notes | This advertisement is between pages 4 and 5 of the Fantastic Four story. |
| Synopsis | An advertisement for www.torpedocomics.com, an on-line comics retailer. |
| Notes | This advertisement is between pages 7 and 8 of the Fantastic Four story. |
| Synopsis | An obituary essay with photograph for Michael Turner. |
| Letters | typeset |
| Notes | This essay is between pages 12 and 13 of the Fantastic Four story. |
| Synopsis | An in-house promotional advertisement for Avengers: The Initiative (Marvel, 2007 series) #16. |
| Notes | This advertisement is between pages 13 and 14 of the Fantastic Four story. |
| Synopsis | An in-house promotional advertisement for Deadpool (Marvel, 2008 series). |
| Notes | This advertisement is between pages 14 and 15 of the Fantastic Four story. |
| Synopsis | An in-house promotional advertisement for Marvel Apes (Marvel, 2008 series). |
| Pencils | R.F. Bachs (signed) |
| Inks | Karl Kesel (signed) |
| Colors | Javier Mena (signed) |
| Notes | This advertisement is between pages 17 and 18 of the Fantastic Four story. |
| Synopsis | An in-house promotional advertisement for Nova (Marvel, 2007 series) #16. |
| Notes | This advertisement is between pages 18 and 19 of the Fantastic Four story. |
| Synopsis | An in-house promotional advertisement for Venom: Dark Origin (Marvel, 2008 series) |
| Notes | This advertisement is between pages 19 and 20 of the Fantastic Four story. |
| Synopsis | An advertisement for Verizon Wireless's games, ringtones, and previews of the Warner Brothers' motion picture, "The Dark Knight." |
| Notes | inside back cover |
| Synopsis | An anti-illegal drug use promotional advertisement from the Office of National Drug Control Policy. |
| Notes | back cover |