| Issue | #2 |
| Published | October 2009 |
| Cover Price | 2.99 USD |
| Pages | 36 |
| Editing | Axel Alonso; Sebastian Girner (Assistant) |
| Characters | Deadpool; Zombie Deadpool |
| Genre | superhero |
| Pencils | Arthur Suydam (Painted) |
| Inks | Arthur Suydam (Painted) |
| Colors | Arthur Suydam (Painted) |
| Letters | Typeset |
| Notes | Cover is a parody of the movie poster for Jaws. |
| Characters | Zombie Deadpool |
| Genre | superhero |
| Pencils | Tony Moore; Jim Cheung |
| Inks | Tony Moore; Jim Cheung |
| Letters | Typeset |
| Notes | Cover has a white background and a border of a number of Marvel characters that is a tribute to the Marvel 25th Anniversary border which appeared on most Marvel books from November 1986. |
| Characters | Deadpool |
| Genre | superhero |
| Pencils | Bong Dazo |
| Inks | Jose Pimentel |
| Colors | Matt Milla |
| Letters | Typeset |
| Notes | 2nd Print variant utilizes interior story panels as the cover image. |
| Characters | Deadpool; GUESTS: Dr. Betty Swanson; Zombie Deadpool; VILLAINS: Hydra; CAMEOS: Ka-Zar; Zabu |
| Synopsis | AIM wants Zombie Deadpool's living head to study and weaponize it and DP and Dr. Betty have to battle rabid cavemen, hungry dinosaurs and nefarious agents of Hydra to get it. |
| Genre | superhero |
| Script | Victor Gischler |
| Pencils | Bong Dazo |
| Inks | Jose Pimentel |
| Colors | Matt Milla |
| Letters | Jeff Eckleberry |
| Notes | Recap page is incorporated into the main story and is included in the page count. |