| Issue | #1 |
| Published | December 2009 |
| Frequency | monthly |
| Cover Price | 3.99 USD |
| Pages | 52 |
| Editing | Stephen Wacker; Tom Brennan (Assistant Editor) |
| Characters | Spider-Man |
| Genre | superhero |
| Pencils | Pascual Ferry (signed) |
| Inks | Pascual Ferry |
| Colors | ? [as fgd] (signed) |
| Characters | Zombie Spider-Man |
| Genre | superhero |
| Pencils | Mirco Pierfederici (painted) |
| Inks | Mirco Pierfederici (painted) |
| Colors | Mirco Pierfederici (painted) |
| Pencils | ? (illustration) |
| Inks | ? (illustration) |
| Colors | ? (illustration) |
| Letters | typeset |
| Notes | Introductory page including table of contents with credits. |
| Characters | Kaine; Spider-Man [Ben Reilly](dream sequence); Jackal [Miles Warren](dream sequence); Peter Parker (dream sequence) |
| Synopsis | Kaine is confined and undergoing experimentation by a group of scientists, who are unaware of the conflicts going on in his mind. |
| Genre | superhero |
| Script | J. M. DeMatteis |
| Pencils | Val Semeiks |
| Inks | Dan Green |
| Colors | Andres Mossa |
| Letters | Dave Lanphear |
| Characters | Spider-Girl [May Parker]; Jersey Devil; Don Silvio [Silverback]; Black Tarantula; April Parker [also appears as Spider-Girl]; Fury [Goblin Queen]; Peter Parker; Captain Margarita Ruiz; Father James Santini |
| Synopsis | After escaping from Don Silvio's thugs, May is attacked by the legendary Jersey Devil, and is later wakened by a priest. Meanwhile, April (who believes May is dead) is web-swinging as Spider-Girl when she is captured by Fury. |
| Genre | superhero |
| Script | Tom DeFalco; Ron Frenz (co-plot) |
| Pencils | Ron Frenz |
| Inks | Sal Buscema |
| Colors | Bruno Hang |
| Letters | Dave Sharpe |
| Editing | Tom Brennan |
| Characters | Spider-Man; Frog-Man [Eugene Patillo]; Tadpole; Kangaroo |
| Synopsis | The tables are turned on Frog-Man when the tenacious Tadpole shows up and wants to be his sidekick. |
| Genre | superhero; humor |
| Script | Sean McKeever |
| Pencils | Stephanie Buscema (painted) |
| Inks | Stephanie Buscema (painted) |
| Colors | Stephanie Buscema (painted) |
| Letters | Jared K. Fletcher |
| Script | Steve Wacker |
| Pencils | various |
| Inks | various |
| Letters | typeset |
| Notes | Explanation of this newest Spider-Man title. Page includes cover reprint of Web of Spider-Man (1985 series) #1 and cover art for upcoming books [Amazing Spider-Man (2003 series) #614; Anti-Venom (2009 series) #2; Clone Saga (2009 series) #2]. |