| Issue | #495 |
| Published | November 2008 |
| Cover Price | 4.99 USD |
| Pages | 52 |
| Editing | John Ficarra |
| Notes | ISSN 024 9319 |
| Characters | Alfred E. Neuman |
| Genre | humor |
| Letters | typeset |
| Notes | ISSN 024 9319 |
| Pencils | ? (photo) |
| Inks | ? (photo) |
| Colors | ? (photo) |
| Letters | typeset |
| Notes | Ad for the movie by Summit Entertainment. On inside front cover. |
| Characters | Alfred E. Neuman; The Joker; John McCain |
| Pencils | various |
| Inks | various |
| Letters | typeset |
| Notes | Art is from various places in the magazine. The feature "Why So Sirius? Department" is phony and does not actually appear in the issue. |
| Characters | Alfred E. Neuman; Black Spy; White Spy; Bill Clinton; Jacobus Dixon; Michael Grinspan; Matt Lassen; Jon Marquis; Aaron Sidorov; Laurie Sanford; Erin Miller |
| Synopsis | Photos of MAD interns. |
| Script | John Ficarra |
| Pencils | ?; ? (photo) |
| Inks | ?; ? (photo) |
| Colors | ?; ? (photo) |
| Letters | typeset |
| Notes | Letters, photos and fan art from : Griffin Benzel; Andrew Rybczynski; Brenner Williams; Christina Collins; Nikki Franda; Evan Caprenter; Ryan Murphy; Bryce Waslak; Tommy La Voy; Jacob McDaniel; Yahawa Ashaqua |
| Letters | typeset |
| Notes | Ad for game from Konami. Appears between pages 1-2 of letters pages. |
| Pencils | ? (photo) |
| Inks | ? (photo) |
| Colors | ? (photo) |
| Letters | typeset |
| Notes | Ad for a Heritage auction. Shows covers of MAD #31, #43, #106, #126 and others. Appears between pages 2-3 of letters pages. |
| Letters | typeset |
| Notes | On 3rd page of letters column. |
| Characters | Jeffrey Lozenge |
| Synopsis | A message on liberty. |
| Script | Jeffrey Lozenge ? |
| Pencils | ? (photo) |
| Inks | ? (photo) |
| Colors | ? (photo) |
| Letters | typeset |
| Notes | House ad for Mad subscriptions; #27 in a series. |
| Characters | Joe Biden; Sarah Palin; John McCain; Joe Bitterman; Bill O'Reilly; John Edwards; Jethro Gruntman; Heinrich von Boffo; Dogstar Zamana; Claxton Baker |
| Synopsis | Various short satires of pop culture. |
| Genre | humor |
| Pencils | various |
| Inks | various |
| Letters | typeset |
| Notes | Contributors (roles unknown) include: Scott Bricher; Tom Bunk; Tom Cheney; Dick DeBartolo; Desmond Devlin; Garth Gerhart; Jeff Kruse; Sam Sisco |
| Characters | Bucky Lasek |
| Synopsis | Ad for AST Dew Tour tv show series. |
| Pencils | Bo Bridges (photo) |
| Inks | Bo Bridges (photo) |
| Colors | Bo Bridges (photo) |
| Letters | typeset |
| Characters | Battyman [Bruce Whine]; The Jokester; Radish Dawson; Harvey Dink; Katie Holmes; Tom Cruse (cameo); Bozo (cameo); Ronald McDonald (cameo); Superman (cameo); Commissioner Walk-on; Neuman; Cookie Monster (cameo) |
| Synopsis | Loosely follows the plot of the movie "The Dark Knight." |
| Genre | satire |
| Script | Desmond Devlin |
| Pencils | Tom Richmond |
| Inks | Tom Richmond |
| Letters | typeset |
| Notes | No name is given for the Morgan Freeman character. |
| Characters | George Bush; Joe Lieberman; Colin Powell; John McCain |
| Synopsis | Fake definitions for words used to describe aspects of the War on Terror. |
| Genre | satire |
| Script | Desmond Devlin |
| Pencils | Paul Coker |
| Inks | Paul Coker |
| Letters | typeset |
| Notes | A follow-up to an article in MAD #438. |
| Synopsis | A look at some possible goofy outcomes of fortune telling. |
| Genre | humor |
| Script | Sergio Aragones |
| Pencils | Sergio Aragones |
| Inks | Sergio Aragones |
| Characters | Alfred E. Neuman |
| Genre | satire |
| Letters | typeset |
| Notes | A parody of the Barack Obama poster "Hope." |
| Characters | Keith Olberman; George W. Bush; John McCain; John Edwards; Andrea Mitchell; Bill O'Reilly |
| Synopsis | Minute-by-minute looks at features on "Countdown" taken to their extremes. |
| Genre | satire |
| Script | Desmond Devlin |
| Pencils | Peter Kuper |
| Inks | Peter Kuper |
| Letters | typeset |
| Characters | Alfred E. Neuman; Bill Clinton |
| Letters | typeset |
| Notes | House ad for MAD Magazine Poster Book and MAD About Politics pop-up book. |
| Characters | John McCain; Thomas Jefferson; James Monroe; Meriwether Lewis; William Clark; Sacagawea; Abraham Lincoln; Betsy Ross; Charles Lindberg; Franklin D. Roosevelt; Joseph Stalin |
| Synopsis | John McCain appears in historic paintings and photos of the past 400 years of American history. |
| Genre | satire |
| Pencils | Scott Bricher; ? (photo) |
| Inks | Scott Bricher; ? (photo) |
| Letters | typeset |
| Notes | Uses some real historic photos as bases for some computer changes. |
| Characters | Monroe; Monroe's mother; Monroe's father; Monroe's grandfather; Walter; Gustavo |
| Synopsis | Monroe's chemistry experiment blows up in class and the FBI takes him in for interrogation as a terrorist suspect. |
| Genre | humor |
| Script | Anthony Barbieri |
| Pencils | Tom Fowler |
| Inks | Tom Fowler |
| Colors | Carl Peterson |
| Genre | humor |
| Script | Ryan Pagelow; Christopher Baldwin; Glen Lelievre;Joey Sayers; Rob Harrell; John Kovaleski; Todd Clark; Douglas Paszkiewicz |
| Pencils | Ryan Pagelow; Christopher Baldwin; Glen Lelievre;Joey Sayers; Rob Harrell; John Kovaleski; Todd Clark; Douglas Paszkiewicz |
| Inks | Ryan Pagelow; Christopher Baldwin; Glen Lelievre;Joey Sayers; Rob Harrell; John Kovaleski; Todd Clark; Douglas Paszkiewicz |
| Letters | Ryan Pagelow; Christopher Baldwin; Glen Lelievre;Joey Sayers; Rob Harrell; John Kovaleski; Todd Clark; Douglas Paszkiewicz |
| Notes | A collection of comic strips. |
| Characters | John McCain; Sarah Palin |
| Synopsis | A parody of movie poster for "Forgetting Sarah Marshall." |
| Genre | satire |
| Pencils | ?; ? (photo) |
| Inks | ?; ? (photo) |
| Colors | ?; ? (photo) |
| Letters | typeset |
| Characters | Michael Jackson; Bubbles |
| Synopsis | A look at the things apes would do wrong if they thought more like people. |
| Genre | humor |
| Script | John Caldwell |
| Pencils | John Caldwell |
| Inks | John Caldwell |
| Letters | typeset |
| Characters | Black Spy; White Spy; Grey Spy |
| Synopsis | The Grey Spy lures the others into a trap, with her feminine wiles. |
| Genre | humor |
| Script | Peter Kuper |
| Pencils | Peter Kuper |
| Inks | Peter Kuper |
| Synopsis | What might happen if common practices in presidential elections were transfered to high schools. |
| Genre | satire |
| Script | Nathaniel Stein |
| Pencils | Jose Garibaldi |
| Inks | Jose Garibaldi |
| Letters | ty |
| Pencils | ? (photo) |
| Inks | ? (photo) |
| Colors | ? (photo) |
| Letters | typeset |
| Notes | Ad for DVDs of tv shows: Little Britain; The Office; Doctor Who; Robin Hood; Spaced; Torchwood |
| Synopsis | Answer is: TMZ. |
| Genre | humor |
| Script | Al Jaffee |
| Pencils | Al Jaffee |
| Inks | Al Jaffee |
| Letters | typeset |
| Notes | Inside back cover. |
| Genre | gags |
| Script | Sergio Aragones |
| Pencils | Sergio Aragones |
| Inks | Sergio Aragones |
| Notes | Gags appear on 11 different pages. |
| Characters | Kane; Undertaker |
| Pencils | ? (photo) |
| Inks | ? (photo) |
| Colors | ? (photo) |
| Letters | typeset |
| Notes | Ad for wrestling DVD with mini-busts bonus figurines, from World Wrestling Entertainment. On back cover. |