| Issue | #300 |
| Published | January 1982 |
| Frequency | monthly |
| Cover Price | 0.60 USD |
| Pages | 36 |
| Editing | Karen Berger |
| Characters | Cain |
| Pencils | Michael W. Kaluta (signed) |
| Inks | Michael W. Kaluta (signed) |
| Characters | Cain; Abel; Eve; Gregory the Gargoyle; Mildred; Mordred; Cynthia |
| Genre | humor |
| Script | Karen Berger |
| Pencils | Joe Orlando |
| Inks | Joe Orlando |
| Genre | science fiction; horror |
| Script | Len Wein |
| Pencils | Gil Kane |
| Inks | Dan Adkins |
| Colors | Adrienne Roy |
| Letters | John Costanza |
| Script | ? [as Cain] |
| Letters | typeset |
| Notes | Letters submitted by Todd McFarlane; T. M. Maple; Jeffrey Lowndes |
| Genre | horror |
| Script | Marv Wolfman |
| Pencils | Joe Staton |
| Inks | Bob Smith |
| Colors | Jerry Serpe |
| Letters | Milt Snapinn |
| Genre | horror |
| Script | Gerry Conway |
| Pencils | Johnny Craig |
| Inks | Johnny Craig |
| Colors | Tatjana Wood |
| Letters | Gaspar Saladino |
| Characters | Cain; Gregory the Gargoyle; Linda Rowley; Mishkin & Cohn [The Two-Headed Writer]; Anabis; Norman |
| Synopsis | The new paper delivery girl gets a look inside the House of Mystery. |
| Genre | humor |
| Script | Dan Mishkin; Gary Cohn |
| Pencils | Adrian Gonzales |
| Inks | Larry Mahlstedt |
| Colors | Jerry Serpe |
| Letters | John Costanza |
| Genre | crime |
| Script | Bruce Jones; April Campbell |
| Pencils | Dan Spiegle |
| Inks | Dan Spiegle |
| Colors | Tatjana Wood |
| Letters | Phil Felix |