| Issue | #61 |
| Published | June 2005 |
| Frequency | monthly |
| Cover Price | 2.25 USD |
| Pages | 48 |
| Editing | Joan Hilty; Rachel Gluckstern (Assistant Editor) |
| Notes | This issue includes an 8-page advertising insert for Heroscape toys from Milton Bradley. |
| Characters | Bubbles; Buttercup; Blossom |
| Genre | superhero; children |
| Pencils | Phil Moy (signed) |
| Inks | Phil Moy |
| Characters | Bubbles; Blossom; Buttercup; Talking Dog; Professor Utonium; Mayor; Sara Bellum (cameo) |
| Synopsis | Bubbles and Talking Dog grow to giant size when they are accidentally struck by a weird ray from a runaway spectra-atomic-ionic meter. |
| Genre | superhero; children |
| Script | Ivan Velez, Jr. |
| Pencils | Phil Moy |
| Inks | Phil Moy |
| Colors | Heroic Age |
| Letters | Pat Brosseau |
| Characters | Blossom; Buttercup; Bubbles; Mayor; Screamin' Steven; Him; Professor Utonium (cameo); Talking Dog (cameo); Sara Bellum (cameo) |
| Synopsis | Popular disk jockey Screamin' Steven can already get the people of Townsville to perform crazy stunts, so Him forces Steven to make them go even further -- to destroy the Powerpuff Girls! |
| Genre | superhero; children |
| Script | Abby Denson |
| Pencils | Christopher Cook |
| Inks | Mike DeCarlo |
| Colors | Heroic Age |
| Letters | Pat Brosseau |
| Genre | fantasy; adventure |
| Script | Ty Templeton |
| Pencils | Joe Phillips |
| Inks | Richard Friend |
| Colors | Wildstorm FX |
| Letters | Rob Leigh |
| Editing | Jaye Gardner |
| Notes | Promotional comic insert for Heroscape toys. |
| Characters | Buttercup; Bubbles; Blossom; Ms. Keane; Mayor; Talking Dog (cameo) |
| Synopsis | After the kids at Pokey Oaks Elementary School watch a safety video, Blossom becomes obsessed with safety, Buttercup gets annoyed with her, and Bubbles just sings the video's theme song over and over. |
| Genre | superhero; children |
| Script | Amy Keating Rogers |
| Pencils | Ricardo Garcia Fuentes |
| Inks | Mike DeCarlo |
| Colors | Heroic Age |
| Letters | Pat Brosseau |
| Script | ? [as Johnny DC] |
| Letters | typeset |
| Notes | Art and letters submitted by Lauren Hopper; Haley Lassiter; Elizabeth Collier; Janisha Sanford; Carolyn Strickland; Taylor Austin |