| Issue | #456 |
| Published | August 2005 |
| Cover Price | 3.99 USD |
| Pages | 56 |
| Editing | John Ficarra |
| Characters | Alfred E. Neuman; The Thing; Invisible Woman; Human Torch |
| Genre | satire |
| Pencils | Mark Fredrickson |
| Inks | Mark Fredrickson |
| Characters | The Thing; Alfred E.Neuman; Yoda; Monroe (All border contents) |
| Synopsis | Table of contents. |
| Genre | satire |
| Synopsis | Letters from Readers and celebs. |
| Genre | satire |
| Characters | Matthew Perry; Jessica Simpson; "Mr.Britney Spears"; Clint Howard; Britney Spears; Melvin; Jenkins; Joe; Nick |
| Synopsis | Quickie Tidbits; gags and cartoons Focusing on People Places and things in politics & pop culture. |
| Genre | Satire |
| Script | Desmond Devlin; Duck Edwing; Drew Friedman; Garth Gerhart; Darren Johnson; Jeff Kruse; Mike Snider; Alan Roberts; |
| Pencils | Ray Alma; Scott Bricher; Paul Coker; Duck Edwing; Gary Hallgren; Scott Mendenhall; Kevin Pope; Tim Shamey; Dennis Snee; Jack Syracuse |
| Inks | Ray Alma; Scott Bricher; Paul Coker; Duck Edwing; Gary Hallgren; Scott Mendenhall; Kevin Pope; Tim Shamey; Dennis Snee; Jack Syracuse |
| Notes | Feature include Celebrity cause-of-death Betting Odds; Animal Housed; The cover we didn't use; Comedy Spotlight; Outtakes; Bitterman; Melvin & Jenkins. |
| Characters | Oldie Von Moldie; Chancellor Palpitation; Barf More; Chewing Tobacco; Bar Stool; Senator AmaDilly; General Greasy; Count Cuckoo; Mannequin Skystalker; Dark Traitor; Yowza; Fail Organic; Laidup; Lace |
| Synopsis | Movie Parody Of Episode III:Revenge Of The Sith. |
| Genre | satire |
| Script | David Shayne |
| Pencils | Herman Mejia |
| Inks | Herman Mejia |
| Characters | White Spy; Black Spy |
| Synopsis | Spy Vs. Spy Regular Feature. |
| Genre | gags |
| Script | Peter Kuper |
| Pencils | Peter Kuper |
| Inks | Peter Kuper |
| Characters | Fantastic Four; Doctor Doom |
| Synopsis | Gags Featuring Photos from The Fantastic Four Movie with humorous text. |
| Genre | gags |
| Notes | No Credits given for feature. |
| Synopsis | Textless Sergio Aragones Feature focusing on Summer Jobs. |
| Genre | gags |
| Script | Sergio Aragones |
| Pencils | Sergio Aragones |
| Inks | Sergio Aragones |
| Synopsis | Pizza Place ad parody featuring mock Coupons and menu. |
| Genre | Humor (comedy) |
| Script | Scott Maiko |
| Pencils | Scott Bricher |
| Inks | Scott Bricher |
| Characters | George W. Bush |
| Synopsis | gags featuring Ways kids can con their way out of any situation using the Policies of President George W. Bush. |
| Genre | satire |
| Script | Mark Cantrell |
| Pencils | Amanda Conner |
| Inks | Amanda Conner |
| Characters | Monroe; Mom; Dad; Grandpa; Baby Perry; Mr.Lentz |
| Synopsis | Monroe Gets left home alone with baby Perry on his Summer Vacation. |
| Genre | Humor (comedy) |
| Script | Anthony Barbieri |
| Pencils | Bill Wray |
| Inks | Bill Wray |
| Synopsis | Mock Exercise equipment ad. |
| Genre | satire |
| Script | Dick DeBartolo |
| Synopsis | Gag focusing on the fine print of a Summer Camp Brochure. |
| Genre | gags |
| Script | John Caldwell |
| Pencils | John Caldwell |
| Inks | John Caldwell |
| Characters | Fantastic Four |
| Synopsis | Gags focusing on the bad times of being a super hero. |
| Genre | gags |
| Script | Johnny Ryan; Greg Leitman |
| Pencils | Johnny Ryan |
| Inks | Johnny Ryan |
| Characters | X-to-the-R X-Rapper |
| Synopsis | Parody of Pimp My Ride. |
| Genre | Satire |
| Script | Dave Croatto |
| Pencils | Tom Richmond |
| Inks | Tom Richmond |
| Synopsis | Another famous Al Jaffee Mad Fold-In. |
| Genre | Satire |
| Script | Al Jaffee |
| Pencils | Al Jaffee |
| Inks | Al Jaffee |