| Issue | #2 |
| Published | May 1991 |
| Cover Price | 1.50 USD; 2.00 CAD |
| Pages | 36 |
| Editing | Jim Salicrup; Dan Cuddy (assistant) |
| Characters | The Toxic Avenger [Melvin Junko]; Claire |
| Genre | Superhero |
| Pencils | Rodney Ramos (signed) |
| Inks | Armando Gil (signed) |
| Characters | The Toxic Avenger [Melvin Junko]; Claire; Mrs. Junko; Police Chief Roddy Hoag; VILLAINS: Darkella; Mr. Chairman; Mr. Ahriman; Ms. Mephi; Eboni; Rust (dies); Red Team [Demos; Luci; Asmo; Drekko; Astarte]; Bahd; Rahd; Mayor Greenspan |
| Synopsis | The Toxic Avenger versus The Red Team. |
| Genre | Superhero |
| Script | Doug Moench |
| Pencils | Rodney Ramos [as Rod Ramos] |
| Inks | Val Mayerik; Al Milgrom; Keith Williams |
| Colors | Bob Sharen |
| Letters | Rick Parker; Jade Moede |
| Script | Stan Lee; ? |
| Letters | typeset |
| Notes | Stan Lee with an April Fools Day joke. The page is filled with other April Fools Day jokes. |
| Characters | Toxic Avenger; Claire |
| Script | Jim Salicrup |
| Pencils | ? (photograph) |
| Inks | ? (photograph) |
| Colors | ? (photograph) |
| Letters | typeset |
| Notes | Jim Salicrup discusses the background behind this series. |