| Issue | #6 |
| Published | May 1992 |
| Cover Price | $2.50 |
| Pages | 36 |
| Editing | David Campiti; George Broderick Jr |
| Notes | The word 'in' is not on the cover! Alpha Control by Bill Mumy |
| Genre | Science Fiction |
| Script | Terry Collins |
| Pencils | Mike Okamoto (painting) [signed as Okamoto92] |
| Inks | Mike Okamoto (painting) [signed as Okamoto92] |
| Colors | Mike Okamoto (painting) [signed as Okamoto92] |
| Notes | The word 'in' is not on the cover! Alpha Control by Bill Mumy |
| Characters | The crew of the Jupiter 2; the Hexagons |
| Synopsis | Crashed on a planet from the last issue, the crew makes repairs and searches for deutronium for fuel. Lodged in the Chariot's secondary intake system is a box of hexagons which can envelop animate and inanimate matter. |
| Genre | Science Fiction |
| Script | Terry Collins |
| Pencils | John Garcia (illustrator) |
| Inks | John Garcia (illustrator) |
| Colors | Scott Rockwell |
| Letters | Vickie Williams |
| Editing | David Campiti; George Broderick Jr. |
| Notes | Story continued in Lost in Space Annual number 1 |
| Synopsis | 1. Memories of the 1st 6 issues 2. Announcement of LIS Special Edition #1, Annual #1, Posters and a Portfolio with art-sized plates by Mike Okamoto 3. Fan letters will start in issue 7 |
| Genre | Editorial |
| Editing | David Campiti Jan 1992 |
| Synopsis | 1. 4 page special preview of Innovation's "Dark Shadows" March '92 2. 1 page ad for Innovation comics on sale this month 3. Promo for Lost in Space Annual #1, continuing the story in issue #6 with cast photos and unpublished art. |
| Synopsis | 1. 2 page add for Backstreet Issues Plus 2. 1 page entry form for Comic Buyer's Guide Fan awards for 1991 |