| Issue | #4 |
| Published | 1988 |
| Cover Price | 1.75 |
| Pages | 68 |
| Characters | High Evolutionary, Magma, Stack, Purge. |
| Genre | superhero |
| Pencils | June Brigman |
| Inks | Bob McLeod |
| Characters | Magneto, Cannonball, Magik, Mirage, Sunspot, Warlock, Wolfsbane; GS: Magma, Empath; V: High Evolutionary, Purifiers, Stack, Purge; GA: Emma Frost, Sebastian Shaw, Selene; OC: Glow Worm, Bulk (both from X-Factor #7, both D), Lucius Antonius Aquilla. |
| Synopsis | The High Evolutionary captures Magma, in the hope of removing her powers; the New Mutants charge to her rescue, along with Magneto and the other members of the Inner Circle of the Hellfire Club. |
| Genre | superhero |
| Script | Louise Simonson |
| Pencils | June Brigman |
| Inks | Bob McLeod |
| Colors | Glynis Oliver |
| Letters | John Workman |
| Editing | Ann Nocenti and Bob Harras (editors); Tom DeFalco (editor-in-chief) |
| Notes | This story occurs between New Mutants #66 and #67. Part of The Evolutionary War crossover with other 1988 annuals. Mirage learns how to make her images become tangible in this story. |
| Characters | Magneto, Cannonball, Magik, Mirage, Sunspot, Warlock, Wolfsbane; SC: Brightwind. |
| Synopsis | Mirage experiments with her new ability to make her images tangible. |
| Genre | superhero |
| Script | Louise Simonson |
| Pencils | June Brigman |
| Inks | Roy Richardson |
| Colors | Glynis Oliver |
| Letters | John Workman |
| Editing | Bob Harras (editor); Tom DeFalco (editor-in-chief) |
| Notes | This story follows on the heels of the previous story in this issue. |
| Characters | Herbert Edgar Wyndham (later: High Evolutionary); SC: Jonathan Drew, Merriem Drew (D), Jessica Drew (later: Spider-Woman); O: Subterraneans, Phillip. |
| Synopsis | While Wyndam is at work in Wundagore Mountain, Jessica Drew, the son of Wyndam's associate Jonathan Drew, develops radiation poisoning; Jonathan develops a spider-serum to help her recover, but before he can use it, his wife Merriem is murdered. |
| Genre | superhero |
| Script | Mark Gruenwald |
| Pencils | Ron Lim |
| Inks | Jim Sinclair |
| Colors | Gregory Wright |
| Letters | Ken Lopez |
| Editing | Ralph Macchio (editor); Tom DeFalco (editor-in-chief) |
| Notes | Part 4 of the saga (origin) of the High Evolutionary, which ran through all of Marvel's 1988 annuals. Origin of Jessica Drew, who later becomes Spider-Woman. Continues in Fantastic Four Annual #21. |