| Issue | #375 |
| Published | March 1993 |
| Frequency | monthly |
| Cover Price | 3.95 USD; 4.95 CAD |
| Pages | 68 |
| Editing | Mike Lackey (Assistant Editor); Danny Fingeroth (Editor); Tom DeFalco (Editor-in-Chief) |
| Characters | Spider-Man; Venom |
| Genre | superhero |
| Pencils | Mark Bagley |
| Inks | Randy Emberlin |
| Notes | Foil enhanced cover |
| Characters | FEATURE: Spider-Man; GUESTS: Richard Parker; Mary Parker; Silver Sable; Wild Pack; J. Jonah Jameson; Anne Weying [Venom's Ex-Wife]; Lance Bannon; Mary Jane Parker; VILLAIN: Venom |
| Synopsis | Venom captures Peter's Parents; JJJ hires Sable and Wild Pack to bring Venom in; Spidey goes to Venom's ex-wife for help; Venom and Spidey call an uneasy truce. |
| Genre | superhero |
| Script | David Michelinie |
| Pencils | Mark Bagley |
| Inks | Randy Emberlin |
| Colors | Bob Sharen |
| Letters | Richard Starkings, Rick Parker |
| Notes | Story leads into Venom's 1st mini-series "Lethal Protector." |
| Characters | FEATURE: Spider-Man; GUESTS: Human Torch; Thing; Mr. Fantastic; Invisible Woman; Silver Sable; Wild Pack; VILLAINS: Dr. Octopus; Sandman; Venom |
| Synopsis | Spidey searches for the Human Torch after the latter blows up Empire State U; Spidey reminisces about his 1st meeting and relationship with Johnny Storm. |
| Genre | superhero |
| Script | Tom DeFalco |
| Pencils | Pat Oliffe |
| Inks | Mark McKenna |
| Colors | Renee Witterstaetter |
| Letters | Dave Sharpe |
| Notes | Story Takes Place Directly After Fantastic Four #373; Continued in FF #374 |
| Characters | FEATURE: John Jameson; GUEST: J. Jonah Jameson; CAMEO: Spider-Man |
| Synopsis | John Jamison saves an Astronaut who is put through a similar disaster that transformed the former into Man-Wolf. |
| Genre | superhero |
| Script | Eric Fein |
| Pencils | Dan Panosian |
| Inks | Dan Panosian |
| Colors | Tom Smith |
| Letters | Joe Rosen |
| Editing | Danny Fingeroth |
| Characters | FEATURE: Chameleon; GUEST: Spider-Man [Chameleon]; VILLAIN: Kraven [Chameleon] |
| Synopsis | Chameleon saves Kraven's grave from vandals and reminisces about his history with the Hunter. |
| Genre | superhero |
| Script | Terry Kavanagh |
| Pencils | Aaron Lopresti |
| Inks | Don Hudson |
| Colors | Renee Witterstaetter |
| Letters | Jon Babcock |