| Issue | #48 |
| Published | July 1959 |
| Cover Price | 0.25 USD |
| Pages | 52 |
| Editing | Albert B. Feldstein |
| Characters | Alfred E. Neuman; Uncle Sam |
| Genre | humor |
| Pencils | Kelly Freas (painted, signed) |
| Inks | Kelly Freas (painted, signed) |
| Colors | Kelly Freas (painted, signed) |
| Letters | typeset |
| Synopsis | Parody of ad for Oasis cigarettes. |
| Genre | satire |
| Pencils | Kelly Freas (painted) |
| Inks | Kelly Freas (painted) |
| Letters | typeset |
| Notes | Inside front cover. |
| Pencils | various |
| Inks | various |
| Letters | typeset |
| Notes | Art is excerpts from this issue. There is a writer credit for Gary Belkin and Bill Dixon, but uncertain what article(s) it is for. |
| Characters | Leonard Brenner |
| Synopsis | House ad for fake straight jacket. |
| Pencils | ? (photo) |
| Inks | ? (photo) |
| Letters | typeset |
| Notes | Leonard is the model with back turned to the reader; named in letters column of MAD #49. |
| Synopsis | House ad for sixth MAD paperback book. |
| Pencils | ? (photo) |
| Inks | ? (photo) |
| Letters | typeset |
| Characters | George A. Orndorff; Seward McCain; Brett Maverick |
| Synopsis | Letters of comment, mostly about issue #46. Barbara Forrester suggest that Alfred's girlfriend be named Moxie Cowznofsky, and the editor agrees. |
| Script | Albert B. Feldstein; Merwyn Nelson; Josh Zerlin; Jack Marin; Alan Peikin; Charles Allen; Joseph Lipari; Tommy LeClair; Ken Luciani; Russ Durham; Howard Arnberg; David Colton; Seward McCain; Jim Fautus; Wayne Montgomery; Jarl Johansson; Barbara Forrester |
| Pencils | ? (photo) |
| Inks | ? (photo) |
| Letters | typeset |
| Synopsis | House ad for MAD subscriptions. |
| Letters | typeset |
| Characters | Alfred E. Neuman |
| Synopsis | House ad for first MAD record album, from RCA Victor. |
| Pencils | ? (photo) |
| Inks | ? (photo) |
| Letters | typeset |
| Characters | Conrad Hilton; Werner Von Braun; Queen Elizabeth II; Prince Philip; Prince Charles; Hymie Rickover; Richard Nixon; Pat Nixon; Gamal Abdel Nasser; Nikita Krushchev; Mrs. Krushchev; Alfred E. Neuman; Jimmy Hoffa; Charles DeGaulle; Hubert Humphrey; Adlai Stevenson; Harry Truman; General Douglas McArthur; Li'l Abner (cameo); Daisy Mae (cameo); Snuffy Smith (cameo); Snuffy's wife (cameo); Kayo Mullins (cameo); Moon Mullins (cameo); Steve Canyon (cameo); Alley Oop (cameo); Beetle Bailey (cameo); Killer (cameo); Pogo (cameo); Howland Owl (cameo); Lucy Van Pelt (cameo); Charlie Brown (cameo) |
| Synopsis | Comic strips about currently famous people, in styles similar to current comic strips. |
| Genre | satire |
| Script | Frank Jacobs |
| Pencils | Wally Wood (signed) |
| Inks | Wally Wood (signed) |
| Letters | typeset |
| Notes | Writer credit from "Totally MAD" CD collection. |
| Synopsis | Ads for organizations that would oppose actual organizations, such as Alcoholics Unanimous, and Committee To Encourage Juvenile Delinquency. |
| Genre | satire |
| Script | Paul Laikin |
| Pencils | Bob Clarke (signed) |
| Inks | Bob Clarke (signed) |
| Letters | typeset |
| Notes | Writer credit from "Totally MAD" CD collection. |
| Synopsis | Problems with skin diving, new developments, and the ultimate return of man to the sea. |
| Genre | satire |
| Script | Dave Berg (signed) |
| Pencils | Dave Berg (signed) |
| Inks | Dave Berg (signed) |
| Letters | typeset |
| Synopsis | A cavewoman who is resistant to being clobbered on the head falls for a man with an unusual approach. |
| Genre | humor |
| Script | Don Martin (signed) |
| Pencils | Don Martin (signed) |
| Inks | Don Martin (signed) |
| Letters | typeset |
| Characters | Sid Caesar; Ed Ralphwards; Progress Hornsby; Euphoria Hornsby; Bosley Mandiville; Shorty Bubble; Doornet Jaguar; One-Stick Haverstraw; Particular Frosty; 7892-450-37; |
| Synopsis | Progress appears on the tv show "For The Life Of You", a parody of "This Is Your Life." |
| Genre | humor |
| Script | Sid Caesar |
| Pencils | Mort Drucker |
| Inks | Mort Drucker |
| Letters | typeset |
| Characters | Charles Groan |
| Synopsis | Defines common bridge terms, gives advice and shows the pitfalls of playing bridge. Includes a phony newspaper bridge column. |
| Genre | satire |
| Script | Al Jaffee |
| Pencils | Bob Clarke |
| Inks | Bob Clarke |
| Letters | typeset |
| Notes | Writer credit from "Totally MAD" CD collection. |
| Synopsis | A man delicately solves the problem of his parrot going to the bathroom in his shirt. |
| Genre | humor |
| Script | Don Martin (signed) |
| Pencils | Don Martin (signed) |
| Inks | Don Martin (signed) |
| Letters | typeset |
| Characters | Bosley Skagg; Penelope Skagg; T. Finster Moody; Felix Farquahr; Lydia Farquahr; Ethel Frong; Herman Frong; Philo Fosdick; Weldon Wembley; Hector Sedgewick; Tommy Goober; Glenn Pladde; Fenwick Gribble |
| Synopsis | Sample of a newspaper that prints all news with a positive spin...no matter how bad the news is. |
| Genre | satire |
| Script | Frank Jacobs |
| Pencils | Joe Orlando |
| Inks | Joe Orlando |
| Letters | typeset |
| Notes | Writer credit from "Totally MAD" CD collection. |
| Synopsis | Spirit and loyalty building songs for various industries' employees, set to familiar melodies. |
| Genre | humor |
| Script | Frank Jacobs |
| Pencils | George Woodbridge (signed) |
| Inks | George Woodbridge (signed) |
| Letters | typeset |
| Characters | Perry Masonmint; Lieutenant Drag; District Attorney Burgerbits; Judge Sam; Paul Dreck; Della Sweet; Harry Townes; Emil Freebish |
| Synopsis | Perry finally loses a case, because he only wins on Saturday nights. |
| Genre | satire |
| Script | Dee Caruso; Bill Levine |
| Pencils | Mort Drucker (signed) |
| Inks | Mort Drucker (signed) |
| Letters | typeset |
| Notes | Parody of Perry Mason tv show. Writer credit from "Totally MAD" CD collection. |
| Characters | Perry Como; Eleanor Roosevelt; Dizzy Gillespe; Oscar Levant; Alfred E. Neuman; Jack Paar |
| Synopsis | Future celebrity confession books. |
| Genre | satire |
| Script | Gary Belkin ? |
| Pencils | George Woodbridge ? |
| Inks | George Woodbridge ? |
| Letters | typeset |
| Characters | Alfred E. Neuman |
| Synopsis | How you might look to people you deal with daily, based on your value to them. |
| Genre | humor |
| Script | Buddy Basch |
| Pencils | Bob Clarke |
| Inks | Bob Clarke |
| Letters | typeset |
| Notes | Writer credit from "Totally MAD" CD collection. |
| Synopsis | Follows a script from the original author through various rewrites, showing how all the meaning and creativity is gradually watered down. |
| Genre | satire |
| Script | Frank Jacobs |
| Pencils | Wally Wood |
| Inks | Wally Wood |
| Letters | typeset |
| Notes | Writer credit from "Totally MAD" CD collection. |
| Characters | Jack Benny; Steve Allen; Ed Sullivan; Dick Clark; Richard Nixon; Fidel Castro |
| Synopsis | Possible graduation speeches that could have helped form the philosophies of some celebrities. |
| Genre | humor |
| Script | Arnie Kogen |
| Pencils | Joe Orlando |
| Inks | Joe Orlando |
| Letters | typeset |
| Notes | Writer credit from "Totally MAD" CD collection. |
| Synopsis | Ideas for insurance policies against common hazards of teen-agers, such as blind dates and flunking school. |
| Genre | humor |
| Script | Sy Reit |
| Pencils | George Woodbridge (signed) |
| Inks | George Woodbridge (signed) |
| Letters | typeset |
| Notes | Writer credit from "Totally MAD" CD collection. |
| Synopsis | The good and bad points of modern synthetic fabrics. |
| Genre | satire |
| Script | Al Jaffee |
| Pencils | Bob Clarke |
| Inks | Bob Clarke |
| Letters | typeset |
| Notes | Writer credit from "Totally MAD" CD collection. |
| Synopsis | An unusual way to play the ball when it lands in a kid's mouth. |
| Genre | humor |
| Script | Don Martin (signed) |
| Pencils | Don Martin (signed) |
| Inks | Don Martin (signed) |
| Letters | typeset |
| Characters | Alfred E. Neuman |
| Synopsis | House ad for hardcover book from Crown Publishers. |
| Pencils | ? (photo); Wally Wood |
| Inks | ? (photo); Wally Wood |
| Letters | typeset |
| Notes | Wally Wood credit is for small image of Alfred at bottom of page. Inside back cover. |
| Synopsis | Casting ideas for remakes of old movies. |
| Genre | humor |
| Letters | typeset |
| Notes | Appear in the margins of 24 pages of the issue. |
| Synopsis | Parody of Parke-Davis Pharmaceutical Company ads. |
| Genre | satire |
| Pencils | Kelly Freas (painted, signed) |
| Inks | Kelly Freas (painted, signed) |
| Colors | Kelly Freas (painted, signed) |
| Letters | typeset |
| Notes | Back cover. |