| Issue | #100 |
| Published | May 2000 |
| Cover Price | $2.99 |
| Pages | 60 |
| Editing | Pete Franco (Assistant); Mark Powers |
| Notes | One of six covers distributed in equal numbers. |
| Characters | Cyclops; Storm; Wolverine; Colossus; Rogue; Nightcrawler; Kitty Pryde |
| Genre | superhero |
| Pencils | Paul Smith |
| Inks | Paul Smith |
| Colors | Dan Kemp |
| Letters | Typeset |
| Notes | One of six covers distributed in equal numbers. |
| Characters | Nightcrawler; Jaeger |
| Genre | superhero |
| Pencils | John Byrne |
| Inks | Mark Morales |
| Letters | Typeset |
| Notes | One of six covers distributed in equal numbers. |
| Characters | Rogue; Seth |
| Genre | superhero |
| Pencils | John Romita Jr. |
| Inks | John Romita Jr. |
| Colors | Dan Kemp |
| Letters | Typeset |
| Notes | One of six covers distributed in equal numbers. |
| Characters | Colossus; Rogue; Psylocke; Nightcrawler; Kitty Pryde; Thunderbird II |
| Genre | superhero |
| Pencils | Leinil Francis Yu |
| Inks | Mark Morales |
| Colors | Liquid Graphics |
| Letters | Typeset |
| Notes | One of six covers distributed in equal numbers. |
| Characters | Jean Grey; Storm; Wolverine; Rogue; Colossus; Nightcrawler; Beast; Psylocke; Gambit; Cable; Thunderbird II; Kitty Pryde |
| Genre | superhero |
| Pencils | Art Adams |
| Inks | Art Adams |
| Letters | Typeset |
| Notes | One of six covers distributed in equal numbers. |
| Characters | Jean Grey; Storm; Wolverine; Colossus; Nightcrawler |
| Genre | superhero |
| Pencils | Dave Cockrum |
| Letters | Typeset |
| Notes | One of six covers distributed in equal numbers. |
| Characters | Colossus; Rogue; Nightcrawler; Gambit; Psylocke; Thunderbird II; Jaeger; Rax |
| Genre | superhero |
| Pencils | Leinil Francis Yu |
| Inks | Mark Morales |
| Colors | Liquid Graphics |
| Letters | Typeset |
| Notes | Retailer variant cover distributed in a ratio of 1:20 to the other alternate covers; There is a Dynamic Forces "Chrome" variant of this cover limited to 3,000 copies. |
| Characters | Wolverine; Storm; Colossus; Psylocke; Rogue; Kitty Pryde |
| Genre | superhero |
| Pencils | Jae Lee |
| Inks | Jae Lee |
| Letters | Typeset |
| Notes | Dynamic Forces alternate cover limited to 7,500 copies. |
| Characters | FEATURE: X-Men--Rogue; Colossus; Nightcrawler; Psylocke; Kitty Pryde; Thunderbird II; Cecilia Reyes [also spelled Cecelia this issue]; GUEST: Dr. Peter Corbeau; VILLAINS: Neo--Domina; Kilmer; Rax; Jaeger (Death); Seth; Elysia; Tartarus; More Unnamed |
| Synopsis | The Neo attack the X-Men both on earth and in space but lose one of their own in the process; Kitty saves the day. |
| Genre | superhero |
| Script | Chris Claremont |
| Pencils | Leinil Francis Yu |
| Inks | Mark Morales |
| Colors | Liquid Graphics |
| Letters | Richard Starkings and Comicraft |
| Characters | FEATURE: Spider-Man; GUESTS: Storm; Iron Man; Wonder Man; Captain America; She-Hulk; Thor; Spider-Girl; Wolverine; Mr. Fantastic; Invisible Woman; Human Torch; The Thing; VILLAIN: Mysterio |
| Genre | superhero |
| Script | Glenn Herdling |
| Pencils | Gregg Schigiel |
| Inks | Richard Case |
| Colors | Paul Mounts |
| Letters | Chris Dickey |
| Editing | Michael Stewart; Steve Behling |
| Notes | Anti-drug story inserted into a number of comics. |