| Issue | #2 |
| Published | September 1990 |
| Frequency | monthly |
| Cover Price | 1.75 USD; 2.25 CAD |
| Pages | 36 |
| Editing | Dan Cuddy (Assistant Editor); Jim Salicrup (Editor); Tom DeFalco (Editor-in-Chief) |
| Characters | Spider-Man; Lizard |
| Genre | Superhero |
| Pencils | Todd McFarlane (signed) |
| Inks | Todd McFarlane (signed) |
| Colors | Todd McFarlane (?) |
| Reprinted | in Star Magazine (Edizioni Star Comics, 1990 series) #8 |
| Characters | Spider-Man [Peter Parker]; Mary Jane Watson-Parker; Villains: Lizard [Curt Connors]; Calypso |
| Synopsis | Spider-Man versus the Lizard. |
| Genre | Superhero |
| Script | Todd McFarlane |
| Pencils | Todd McFarlane |
| Inks | Todd McFarlane |
| Colors | Bob Sharen |
| Letters | Rick Parker |
| Reprinted | in Spider-Man: Torment (Marvel, 1992 series) #[nn]; in Star Magazine (Edizioni Star Comics, 1990 series) #8 |
| Genre | Superhero |
| Script | Jim Salicrup |
| Letters | Typeset |
| Notes | Jim Salicrup discusses Spider-Man (1990) #1 breaking sales records and future stories. |