| Issue | #1 |
| Published | September 2003 |
| Cover Price | $2.25 |
| Pages | 36 |
| Editing | Axel Alonso (Supervising); John Miesegaes |
| Characters | Spider-Man; Venom |
| Genre | superhero |
| Pencils | Humberto Ramos |
| Inks | Wayne Faucher |
| Characters | FEATURE: Spider-Man; GUESTS: Aunt May; Flash Thompson; Liz Osborn; Neil Garrett; VILLAINS: Venom; Eddie Brock |
| Synopsis | Detective Garrett investigates a series of murders where all of the victims have puncture marks on their backs and their bodies have been stripped clean of adrenaline; Eddie seeks forgiveness from a priest for past sins; Peter, May and Liz gather at the hospital to watch the bandages being taken off of the face of the badly injured and mostly comatose Flash Thompson; Spidey gets into a brawl with Venom, only to find out that the symbiote is traveling around without its human host. |
| Genre | superhero |
| Script | Paul Jenkins |
| Pencils | Humberto Ramos |
| Inks | Wayne Faucher |
| Colors | Studio F |
| Letters | Randy Gentile |