| Issue | #16 |
| Published | November 2006 |
| Cover Price | 2.99 USD; 3.35 CAD |
| Pages | 36 |
| Editing | ? |
| Characters | Manticore [Justin Sinclair]; Positron; Sister Psyche; Statesman; Synapse; Anti-Matter; Chimera; Mother Mayhem; Neuron; Tyrant |
| Genre | Superhero |
| Pencils | David Nakayama |
| Colors | Kevin Senft [as Blond] |
| Characters | Manticore [Justin Sinclair]; Positron; Sister Psyche; Statesman; Synapse; Ms. Liberty; Anti-Matter; Chimera; Dominatrix; Malaise; Marauder; Mother Mayhem; Neuron; Tyrant |
| Genre | Superhero |
| Script | Sean Michael Fish |
| Pencils | David Nakayama |
| Colors | Kevin Senft [as Blond] |
| Letters | Troy Peteri |
| Letters | Typeset |
| Notes | A table of contents for the text pieces set up in a faux tabloid newspaper format. |
| Genre | Superhero |
| Script | Charles Lemne |
| Letters | Typeset |
| Genre | Superhero |
| Script | Brian Gilmore; Jesse Scoble |
| Letters | Typeset |
| Letters | Typeset |
| Genre | Humor |
| Script | Aaron Williams |
| Pencils | Aaron Williams |
| Inks | Aaron Williams |
| Colors | Aaron Williams |
| Letters | Aaron Williams |
| Letters | Typeset |
| Notes | The text notes that the submission guide lines are now on-line as opposed to being printed in each issue. |
| Synopsis | [inside front] In house -- Top Cow Productions; [16-17] In house -- City of Villains (game); [inside back] In house -- www.topcowstore.com; [back] In house -- PhysX by ageia |