| Issue | #2 |
| Published | December 1952-January 1953 |
| Cover Price | 0.10 USD |
| Pages | 36 |
| Editing | Harvey Kurtzman |
| Notes | Cover based on the story, "Hex!". |
| Characters | Casey; Old Dame |
| Genre | Satire |
| Pencils | Jack Davis |
| Inks | Jack Davis |
| Colors | Marie Severin |
| Notes | Cover based on the story, "Hex!". |
| Reprinted | In Tales Calculated To Drive You Mad (EC, 1997 series) #1 (Summer 1997) |
| Pencils | Al Feldstein (signed) |
| Inks | Al Feldstein (signed) |
| Letters | typeset |
| Notes | House ad for Weird Fantasy #16. On inside front cover. |
| Characters | Casey; Yeggi Bora; Leo; the Old Dame; Stan Musical; Preacher Rowboat; Eddy Stunky; Melvin Demoogio |
| Synopsis | Casey's team wins the pennant but loses Casey to the Old Dame. |
| Genre | humor; occult |
| Pencils | Jack Davis |
| Inks | Jack Davis |
| Colors | Marie Severin |
| Reprinted | in Tales Calculated to Drive You Mad (EC, 1997 series) #1 |
| Characters | Melvin of The Apes; Boy; Jane; Ookaballakonga tribe |
| Synopsis | Melvin escapes from the Ookaballakonga tribe with the help of the jungle animals but the tribe shrinks Boy's head. |
| Genre | Satire |
| Pencils | John Severin |
| Inks | John Severin |
| Colors | Marie Severin |
| Notes | A parody of Tarzan. |
| Reprinted | in Tales Calculated to Drive You Mad (EC, 1997 series) #1 |
| Colors | Marie Severin |
| Letters | typeset |
| Notes | House ad for E.C. comics. Printed as two ½ pages in bookend fashion around text story sequence. |
| Characters | Monongahela Wheeler; Bablou O'Brien; Lady-In-Mascara; Max; Minx |
| Synopsis | Mo Wheeler believes he's solving a crime but the Lady leads him to a morning radio interview instead. |
| Genre | humor |
| Colors | rgrose@saginawtownship.net |
| Letters | typeset |
| Reprinted | in Tales Calculated to Drive You Mad (EC, 1997 series) #4 |
| Characters | Cosmo McMoon; F. M. Wavelength; Walla-Walla Bazinski; Croton-on-the-Hudson Bazinski; Baden-Baden Bazinski |
| Synopsis | Cosmo discovers a baby who is blending all radio broadcasts into a single program. |
| Genre | Satire |
| Colors | Marie Severin |
| Letters | typeset |
| Reprinted | In Tales Calculated To Drive You Mad (EC, 1997 series) #1 |
| Characters | Glarf Nerfnick; Glarf's grandfather; Melvin |
| Synopsis | A Martian escapes the Gookum on his home planet only to find it apparently exists on Earth also. |
| Genre | science fiction; humor |
| Pencils | Wally Wood [as Melvin Wood] |
| Inks | Wally Wood [as Melvin Wood] |
| Colors | Marie Severin |
| Reprinted | In Tales Calculated To Drive You Mad (EC, 1997 series) #1 |
| Characters | Melvin Mole |
| Synopsis | Melvin is captured during a bank robbery and continually digs his way out of jail. |
| Genre | humor |
| Script | Harvey Kurtzman |
| Pencils | Bill Elder |
| Inks | Bill Elder |
| Colors | Marie Severin |
| Reprinted | in MAD (EC, 1952 series) #22 [with splash panel omitted]; in Tales Calculated to Drive You Mad (EC, 1997 series) #1; in Mad About the Fifties (Little, Brown & Co., 1997 series) #[nn] |
| Letters | typeset |
| Notes | Ad for combination cigarette lighter / cigarettee case. |
| Characters | J. E. Smith |
| Pencils | ? (photo) |
| Inks | ? (photo) |
| Letters | typeset |
| Notes | Ad for tv and radio repair training. On inside back cover. |
| Characters | Charles Atlas |
| Pencils | ? (photo) |
| Inks | ? (photo) |
| Letters | typeset |
| Notes | Ad for body-building course. On back cover. |