| Issue | #21 |
| Published | Winter 1988 |
| Frequency | four times annually |
| Cover Price | 3.50 USD; 4.50 CAD |
| Pages | 60 |
| Editing | Kathe Todd |
| Pencils | Gilbert Shelton |
| Inks | Gilbert Shelton |
| Colors | Guy Colwell |
| Notes | The words "Rip Off" in title also have small images of characters in/on the letters. |
| Script | Kathe Todd |
| Letters | Typeset |
| Notes | Introductory text with a listing of the contents of the issue. |
| Pencils | ? (title logo) |
| Inks | ? (title logo) |
| Letters | Typeset |
| Notes | Title logo with indicia information at bottom of page. |
| Script | Jack Jackson [as Jaxon] |
| Pencils | Jack Jackson [as Jaxon] |
| Inks | Jack Jackson [as Jaxon] |
| Letters | Jack Jackson [as Jaxon] |
| Synopsis | History of Rip Off Press up through 1987 with black and white photoes. |
| Script | Fred Todd |
| Pencils | ? (photographs) |
| Inks | ? (photographs) |
| Letters | Typeset |
| Characters | Uncle Joe |
| Script | Joshua Quagmire |
| Pencils | Joshua Quagmire |
| Inks | Joshua Quagmire |
| Letters | Joshua Quagmire |
| Letters | Typeset |
| Notes | Text with images of art used in Rip Off Press publications over the years. |
| Script | Gilbert Shelton |
| Pencils | Gilbert Shelton |
| Inks | Gilbert Shelton |
| Letters | Gilbert Shelton |
| Letters | Typeset |
| Notes | Two example pages of "Rip Off Comix Syndicate News." |
| Pencils | Gilbert Shelton |
| Inks | Gilbert Shelton |
| Letters | Typeset |
| Notes | Illustration with descriptive text underneath. |
| Script | Kathe Todd |
| Pencils | Kathe Todd |
| Inks | Kathe Todd |
| Letters | Kathe Todd |
| Characters | Freak Brothers |
| Pencils | Gilbert Shelton |
| Inks | Gilbert Shelton |
| Letters | Gilbert Shelton |
| Script | Guy Colwell |
| Pencils | Guy Colwell |
| Inks | Guy Colwell |
| Letters | Guy Colwell |
| Characters | Janis Joplin; Jimi Hendrix |
| Script | Ronn Foss |
| Pencils | Ronn Foss |
| Inks | Ronn Foss |
| Letters | Ronn Foss |
| Characters | Wonder Wart-hog |
| Script | Trina Robbins |
| Pencils | Trina Robbins |
| Inks | Trina Robbins |
| Letters | Trina Robbins |
| Letters | Typeset |
| Notes | Text article with cover reproductions of "The Rip Off Review of Western Culture", "Rip Off Comix" #1-10, "Rip Off" #11-13 (though #13 was never published) and "The New Rip Off Comix" #14-20. |
| Script | Frank Stack [as Foolbert Sturgeon] |
| Pencils | Frank Stack [as Foolbert Sturgeon] |
| Inks | Frank Stack [as Foolbert Sturgeon] |
| Letters | Frank Stack [as Foolbert Sturgeon] |
| Script | Jim Siergey |
| Pencils | Jim Siergey |
| Inks | Jim Siergey |
| Letters | Jim Siergey |
| Script | Manuel Rodriguez [as Spain] |
| Pencils | Manuel Rodriguez [as Spain] |
| Inks | Manuel Rodriguez [as Spain] |
| Letters | Manuel Rodriguez [as Spain] |
| Characters | Fat Freddy's Cat; Freak Brothers; Zippy the Pinhead |
| Script | Paul Mavrides |
| Pencils | Paul Mavrides |
| Inks | Paul Mavrides |
| Letters | Typeset; Paul Mavrides |
| Notes | Text article interview from Knockabout Comic, London, England and "two jam strips done by Paul and whichever other zany cartoonist happened to be around at the time." |
| Script | Ace Backwords |
| Pencils | Ace Backwords |
| Inks | Ace Backwords |
| Letters | Ace Backwords |
| Characters | Cherry Poptart |
| Script | Larry Welz |
| Pencils | Larry Welz |
| Inks | Larry Welz |
| Letters | Larry Welz |
| Notes | Cherry Poptart appears, un-named, in first panel only. |
| Characters | Zippy the Pinhead |
| Script | Bill Griffith |
| Pencils | Bill Griffith |
| Inks | Bill Griffith |
| Letters | Bill Griffith |
| Characters | Miami Mice |
| Script | Mark Bode |
| Pencils | Mark Bode |
| Inks | Mark Bode |
| Letters | Mark Bode |
| Script | R. L. Crabb |
| Pencils | R. L. Crabb |
| Inks | R. L. Crabb |
| Letters | R. L. Crabb |
| Notes | Advertisements used in Rip Off Press publications. |
| Characters | Jesus; Dr. Feelgood; Dorman's Doggie |
| Script | Frank Stack [as Foolbert Sturgeon] |
| Pencils | Frank Stack [as Foolbert Sturgeon] |
| Inks | Frank Stack [as Foolbert Sturgeon] |
| Letters | Frank Stack [as Foolbert Sturgeon] |
| Script | Joshua Quagmire |
| Pencils | Joshua Quagmire |
| Inks | Joshua Quagmire |
| Letters | Joshua Quagmire |
| Letters | Typeset |
| Notes | List of stores that sell Rip Off Press publications. |
| Pencils | Gilbert Shelton |
| Inks | Gilbert Shelton |
| Letters | Typeset |
| Notes | Image one back cover of issue. |