| Issue | #21 |
| Published | October-November 1965 |
| Frequency | Bi-Monthly |
| Cover Price | 0.12 USD |
| Pages | 36 |
| Editing | Julius Schwartz |
| Characters | The Atom [Ray Palmer] |
| Genre | superhero |
| Pencils | Gil Kane |
| Inks | Murphy Anderson |
| Characters | The Atom [Ray Palmer]; Dr. Loring; Jean Loring; Professor Vasiliev (villain) |
| Genre | superhero |
| Script | Gardner Fox |
| Pencils | Gil Kane |
| Inks | Sid Greene |
| Notes | Credits for script, pencils and inks confirmed from Julius Schwartz's editorial records, provided by DC Comics. |
| Notes | Follows page 6 of sequence 1. Followed by sequence 3. |
| Notes | Follows sequence 2. Followed by sequence 4. |
| Genre | humor |
| Script | Henry Boltinoff (signed) |
| Pencils | Henry Boltinoff (signed) |
| Inks | Henry Boltinoff (signed) |
| Notes | Follows sequence 3. Followed by sequence 5. |
| Characters | AMT Kat; George Barris |
| Notes | Follows sequence 4. Followed by page 7 of sequence 1. |
| Characters | Rocky; Bullwinkle |
| Genre | funny animals |
| Script | Julius Schwartz [as The Editor] |
| Letters | Typeset |
| Notes | Letters of comment from readers Paul Bakulski, Mike Friedrich and Andrew Fraknoi, with replies from Schwartz. |
| Characters | The Atom [Ray Palmer]; Henry Fielding; Professor Alpheus V. Hyatt; Theodore Hyatt; Alfred Hyatt; Reddy Bolins (villain); John Fielding |
| Synopsis | In a "Time Pool" story, the Atom meets Henry Fielding. |
| Genre | superhero |
| Script | Gardner Fox |
| Pencils | Gil Kane |
| Inks | Sid Greene |
| Notes | Credits for script, pencils and inks confirmed from Julius Schwartz's editorial records, provided by DC Comics. |
| Characters | Trix |
| Genre | funny animals |
| Notes | Advertisement for the General Mills cereal. |
| Genre | humor |
| Script | Henry Boltinoff (signed) |
| Pencils | Henry Boltinoff (signed) |
| Inks | Henry Boltinoff (signed) |