| Issue | #52 |
| Published | September 2004 |
| Frequency | monthly |
| Cover Price | 2.25 USD |
| Pages | 36 |
| Editing | Joan Hilty; Harvey Richards (Assistant Editor) |
| Characters | Bubbles; Blossom; Buttercup; Princess Morbucks; Miss Keane |
| Genre | superhero; children |
| Pencils | Phil Moy (signed) |
| Inks | Phil Moy |
| Characters | Buttercup; Blossom; Bubbles; Princess Morbucks; Miss Keane; Mitch Mitchelson |
| Synopsis | Princess Morbucks puts Miss Keane and the Powerpuff Girls into an electric cage so that recess can go on all day. |
| Genre | superhero; children |
| Script | Abby Denson |
| Pencils | Ricardo Garcia Fuentes |
| Inks | Mike DeCarlo |
| Colors | Heroic Age |
| Letters | Pat Brosseau |
| Characters | Blossom; Bubbles; Buttercup; Miss Keane; Mitch Mitchelson; Professor Utonium |
| Synopsis | Buttercup's art project, a clay robot, is brought to life when struck by lightning and goes on a rampage. |
| Genre | superhero; children |
| Script | Ivan Velez, Jr. |
| Pencils | Ricardo Garcia Fuentes |
| Inks | Mike DeCarlo |
| Colors | Heroic Age |
| Letters | Pat Brosseau |
| Characters | Bubbles; Blossom; Buttercup; Fuzzy Lumpkins; Professor Utonium |
| Synopsis | Fuzzy Lumpkins has a bad cold, which puts him in a bad mood, and he passes his cold on to the people of Townsville. |
| Genre | superhero; children |
| Script | Robbie Busch |
| Pencils | Ricardo Garcia Fuentes |
| Inks | Mike DeCarlo |
| Colors | Heroic Age |
| Letters | Pat Brosseau |